Semaglutide → Diarrhoea — Audit-grade candidate (scan)

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Ledger entry · candidate

Semaglutide → Diarrhoea — Audit-grade candidate (scan)

Drug: semaglutide · AE: Diarrhoea

Discovered via single-drug scan of semaglutide. PRR = 2.83 (95% CI 2.72–2.94), n = 2315 cases. Pre-reg locked at submission time.

Disproportionality

PRR: 2.83065338408941 (95% CI 2.72–2.94)
Yates χ²: 2817.7507372097743
Cases (case-drug + AE): n = 2315
Verdict: PASSES_ALL_GATES — PRR=2.83 (95% CI 2.72–2.94), n=2315 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

MedDRA PT	n
No reactions surfaced in cohort.

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.

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Reference: e4685ee2e0247dc6f5ee37e1ddded37a47660bdb