Canagliflozin → Blood glucose increased — Audit-grade candidate (class scan)

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Ledger entry · candidate

Canagliflozin → Blood glucose increased — Audit-grade candidate (class scan)

Drug: canagliflozin · AE: Blood glucose increased

Discovered via class scan of SGLT2 inhibitors. PRR = 4.59, n = 1095 cases.

Disproportionality

PRR: 4.590870201858217
Yates χ²: n/a
Cases (case-drug + AE): n = 1095
Verdict: PASSES_ALL_GATES — PRR=4.59 (95% CI 4.33–4.87), n=1095 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

MedDRA PT	n
No reactions surfaced in cohort.

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.

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Reference: c735f396d077177baf528bc7a404a474e1c23465