Hydroxychloroquine → Fatigue — Audit-grade candidate (scan)

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Ledger entry · candidate

Hydroxychloroquine → Fatigue — Audit-grade candidate (scan)

Drug: hydroxychloroquine · AE: Fatigue

Discovered via single-drug scan of hydroxychloroquine. PRR = 2.23 (95% CI 2.14–2.32), n = 2196 cases. Pre-reg locked at submission time.

Disproportionality

PRR: 2.2296635210125517 (95% CI 2.14–2.32)
Yates χ²: 1542.2198218794692
Cases (case-drug + AE): n = 2196
Verdict: PASSES_ALL_GATES — PRR=2.23 (95% CI 2.14–2.32), n=2196 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

MedDRA PT	n
No reactions surfaced in cohort.

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.

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Reference: a5d5913cdc07eb8c7ff2b5084778e63e6f627df8