Hydroxychloroquine → Condition aggravated — Audit-grade candidate (scan)

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Ledger entry · candidate

Hydroxychloroquine → Condition aggravated — Audit-grade candidate (scan)

Drug: hydroxychloroquine · AE: Condition aggravated

Discovered via single-drug scan of hydroxychloroquine. PRR = 4.13 (95% CI 3.94–4.34), n = 1561 cases. Pre-reg locked at submission time.

Disproportionality

PRR: 4.1335758728266505 (95% CI 3.94–4.34)
Yates χ²: 3739.7246173407216
Cases (case-drug + AE): n = 1561
Verdict: PASSES_ALL_GATES — PRR=4.13 (95% CI 3.94–4.34), n=1561 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

MedDRA PT	n
No reactions surfaced in cohort.

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.

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Reference: 9841222b43a1851038ec8def72b256707ae3b392