Dapagliflozin → Weight decreased — Audit-grade candidate (class scan)

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Ledger entry · candidate

Dapagliflozin → Weight decreased — Audit-grade candidate (class scan)

Drug: dapagliflozin · AE: Weight decreased

Discovered via class scan of SGLT2 inhibitors. PRR = 3.80, n = 1333 cases.

Disproportionality

PRR: 3.797594046475963
Yates χ²: n/a
Cases (case-drug + AE): n = 1333
Verdict: PASSES_ALL_GATES — PRR=3.80 (95% CI 3.60–4.00), n=1333 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

MedDRA PT	n
No reactions surfaced in cohort.

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.

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Reference: 8c7aa8d6b4081c0de049a9871e40c87e9e7a3878