Clozapine → Hospitalisation — Audit-grade candidate (scan)

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Ledger entry · candidate

Clozapine → Hospitalisation — Audit-grade candidate (scan)

Drug: clozapine · AE: Hospitalisation

Discovered via single-drug scan of clozapine. PRR = 19.55 (95% CI 18.96–20.15), n = 3641 cases. Pre-reg locked at submission time.

Disproportionality

PRR: 19.546668279309788 (95% CI 18.96–20.15)
Yates χ²: 62927.46093831695
Cases (case-drug + AE): n = 3641
Verdict: PASSES_ALL_GATES — PRR=19.55 (95% CI 18.96–20.15), n=3641 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

MedDRA PT	n
No reactions surfaced in cohort.

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.

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Reference: 61623c1f2459020821f567f11334da129a3f7639