Empagliflozin → Weight decreased — Audit-grade candidate (class scan)

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Ledger entry · candidate

Empagliflozin → Weight decreased — Audit-grade candidate (class scan)

Drug: empagliflozin · AE: Weight decreased

Discovered via class scan of SGLT2 inhibitors. PRR = 3.80, n = 1334 cases.

Disproportionality

PRR: 3.8004570478565225
Yates χ²: n/a
Cases (case-drug + AE): n = 1334
Verdict: PASSES_ALL_GATES — PRR=3.80 (95% CI 3.61–4.00), n=1334 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

MedDRA PT	n
No reactions surfaced in cohort.

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.

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Reference: 27de7a3f42dba7a04339fb52a6c9d3994f2222b7