Hydroxychloroquine → Headache — Audit-grade candidate (scan)

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Ledger entry · candidate

Hydroxychloroquine → Headache — Audit-grade candidate (scan)

Drug: hydroxychloroquine · AE: Headache

Discovered via single-drug scan of hydroxychloroquine. PRR = 2.07 (95% CI 1.98–2.17), n = 1664 cases. Pre-reg locked at submission time.

Disproportionality

PRR: 2.0702535151049917 (95% CI 1.98–2.17)
Yates χ²: 946.4238488222747
Cases (case-drug + AE): n = 1664
Verdict: PASSES_ALL_GATES — PRR=2.07 (95% CI 1.98–2.17), n=1664 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

MedDRA PT	n
No reactions surfaced in cohort.

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.

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Reference: 1aff618f9ad1fac35847560c947f8d7362a4dcb4