Semaglutide → Vomiting — Audit-grade candidate (scan)

Drug: semaglutide · AE: Vomiting

Discovered via single-drug scan of semaglutide. PRR = 4.23 (95% CI 4.08–4.40), n = 2516 cases. Pre-reg locked at submission time.

Disproportionality

• PRR: 4.234364025361064 (95% CI 4.08–4.40)
• Yates χ²: 6323.677189815963
• Cases (case-drug + AE): n = 2516
• Verdict: PASSES_ALL_GATES — PRR=4.23 (95% CI 4.08–4.40), n=2516 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.