Ledger entry · candidate
Varenicline → Sneezing — Audit-grade candidate (scan)
Drug: varenicline · AE: Sneezing
Discovered via single-drug scan of varenicline. PRR = 27.61 (95% CI 25.70–29.67), n = 752 cases. Pre-reg locked at submission time.
Disproportionality
- PRR: 27.6138587286238
(95% CI 25.70–29.67)
- Yates χ2: 18614.03459439478
- Cases (case-drug + AE): n = 752
- Verdict:
PASSES_ALL_GATES — PRR=27.61 (95% CI 25.70–29.67), n=752 cases; flagged for clinical expert review, NOT for external escalation without manual verification
Top reactions in cohort
| MedDRA PT | n |
|---|
| No reactions surfaced in cohort. |
Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.