Ledger entry · candidate
Semaglutide → Decreased appetite — Audit-grade candidate (scan)
Drug: semaglutide · AE: Decreased appetite
Discovered via single-drug scan of semaglutide. PRR = 5.65 (95% CI 5.39–5.92), n = 1637 cases. Pre-reg locked at submission time.
Disproportionality
- PRR: 5.651751212196847
(95% CI 5.39–5.92)
- Yates χ2: 6287.634815912135
- Cases (case-drug + AE): n = 1637
- Verdict:
PASSES_ALL_GATES — PRR=5.65 (95% CI 5.39–5.92), n=1637 cases; flagged for clinical expert review, NOT for external escalation without manual verification
Top reactions in cohort
| MedDRA PT | n |
|---|
| No reactions surfaced in cohort. |
Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.