Hydroxychloroquine → Drug ineffective — Audit-grade candidate (scan)

Drug: hydroxychloroquine · AE: Drug ineffective

Discovered via single-drug scan of hydroxychloroquine. PRR = 3.92 (95% CI 3.84–4.01), n = 6766 cases. Pre-reg locked at submission time.

Disproportionality

• PRR: 3.923592194720422 (95% CI 3.84–4.01)
• Yates χ²: 15707.403164137742
• Cases (case-drug + AE): n = 6766
• Verdict: PASSES_ALL_GATES — PRR=3.92 (95% CI 3.84–4.01), n=6766 cases; flagged for clinical expert review, NOT for external escalation without manual verification

Top reactions in cohort

Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.