Ledger entry · candidate
Clozapine → White blood cell count decreased — Audit-grade candidate (scan)
Drug: clozapine · AE: White blood cell count decreased
Discovered via single-drug scan of clozapine. PRR = 7.01 (95% CI 6.58–7.46), n = 954 cases. Pre-reg locked at submission time.
Disproportionality
- PRR: 7.0052107497171106
(95% CI 6.58–7.46)
- Yates χ2: 4886.615416777813
- Cases (case-drug + AE): n = 954
- Verdict:
PASSES_ALL_GATES — PRR=7.01 (95% CI 6.58–7.46), n=954 cases; flagged for clinical expert review, NOT for external escalation without manual verification
Top reactions in cohort
| MedDRA PT | n |
|---|
| No reactions surfaced in cohort. |
Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.