Ledger entry · candidate
Hydroxychloroquine → Fatigue — Audit-grade candidate (scan)
Drug: hydroxychloroquine · AE: Fatigue
Discovered via single-drug scan of hydroxychloroquine. PRR = 2.23 (95% CI 2.14–2.32), n = 2196 cases. Pre-reg locked at submission time.
Disproportionality
- PRR: 2.2296635210125517
(95% CI 2.14–2.32)
- Yates χ2: 1542.2198218794692
- Cases (case-drug + AE): n = 2196
- Verdict:
PASSES_ALL_GATES — PRR=2.23 (95% CI 2.14–2.32), n=2196 cases; flagged for clinical expert review, NOT for external escalation without manual verification
Top reactions in cohort
| MedDRA PT | n |
|---|
| No reactions surfaced in cohort. |
Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.