Ledger entry · candidate
Semaglutide → Weight decreased — Audit-grade candidate (scan)
Drug: semaglutide · AE: Weight decreased
Discovered via single-drug scan of semaglutide. PRR = 4.70 (95% CI 4.49–4.93), n = 1648 cases. Pre-reg locked at submission time.
Disproportionality
- PRR: 4.700490852527476
(95% CI 4.49–4.93)
- Yates χ2: 4833.625206565303
- Cases (case-drug + AE): n = 1648
- Verdict:
PASSES_ALL_GATES — PRR=4.70 (95% CI 4.49–4.93), n=1648 cases; flagged for clinical expert review, NOT for external escalation without manual verification
Top reactions in cohort
| MedDRA PT | n |
|---|
| No reactions surfaced in cohort. |
Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.