Ledger entry · candidate
Clozapine → Treatment noncompliance — Audit-grade candidate (scan)
Drug: clozapine · AE: Treatment noncompliance
Discovered via single-drug scan of clozapine. PRR = 8.58 (95% CI 7.91–9.30), n = 580 cases. Pre-reg locked at submission time.
Disproportionality
- PRR: 8.575159180035913
(95% CI 7.91–9.30)
- Yates χ2: 3840.977483216887
- Cases (case-drug + AE): n = 580
- Verdict:
PASSES_ALL_GATES — PRR=8.58 (95% CI 7.91–9.30), n=580 cases; flagged for clinical expert review, NOT for external escalation without manual verification
Top reactions in cohort
| MedDRA PT | n |
|---|
| No reactions surfaced in cohort. |
Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.