Ledger entry · candidate
Clozapine → Schizophrenia — Audit-grade candidate (scan)
Drug: clozapine · AE: Schizophrenia
Discovered via single-drug scan of clozapine. PRR = 71.91 (95% CI 67.59–76.52), n = 1052 cases. Pre-reg locked at submission time.
Disproportionality
- PRR: 71.91482196394101
(95% CI 67.59–76.52)
- Yates χ2: 67244.4072698432
- Cases (case-drug + AE): n = 1052
- Verdict:
PASSES_ALL_GATES — PRR=71.91 (95% CI 67.59–76.52), n=1052 cases; flagged for clinical expert review, NOT for external escalation without manual verification
Top reactions in cohort
| MedDRA PT | n |
|---|
| No reactions surfaced in cohort. |
Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.