Ledger entry · candidate
Semaglutide → Nausea — Audit-grade candidate (scan)
Drug: semaglutide · AE: Nausea
Discovered via single-drug scan of semaglutide. PRR = 4.33 (95% CI 4.21–4.45), n = 4287 cases. Pre-reg locked at submission time.
Disproportionality
- PRR: 4.331382028347541
(95% CI 4.21–4.45)
- Yates χ2: 11353.559932083559
- Cases (case-drug + AE): n = 4287
- Verdict:
PASSES_ALL_GATES — PRR=4.33 (95% CI 4.21–4.45), n=4287 cases; flagged for clinical expert review, NOT for external escalation without manual verification
Top reactions in cohort
| MedDRA PT | n |
|---|
| No reactions surfaced in cohort. |
Source: openFDA FAERS, Caliper Engine v0. Pre-registration sha1 locked at submission time; ledger entry signed with platform Ed25519 key.